Recent research from Sydney University has revealed intriguing links between depression and disrupted circadian rhythms, akin to the effects of jet lag. A study, which involved 69 young individuals undergoing mental health treatment, found that about 25% exhibited symptoms typically associated with jet lag, despite not having travelled across time zones.
The study investigated participants aged 16 to 35, divided into two groups – one with mental health issues and the other without. Each participant was monitored overnight in a chronobiology lab to assess their sleep patterns and body clocks.
Researchers, led by Dr. Joanne Carpenter, examined vital indicators such as core body temperature, cortisol, and melatonin levels, all crucial for regulating the body’s circadian rhythm, which governs sleep and wakefulness. Melatonin signals sleep, while cortisol, often peaking shortly after waking, is linked to stress. Body temperature varies according to sleep cycles, and the study found that 23% of the participants’ rhythms were misaligned, similar to the disruptions experienced when travelling or working shifts.
Dr. Carpenter noted a correlation between the degree of circadian disruption and the severity of depressive symptoms in the participants, indicating that mood disorders might be linked to dysfunctional body clocks.
Co-author Dr. Jacob Crouse highlighted the potential implications of these findings for mental health treatment strategies, suggesting that targeting circadian rhythms might offer new avenues for managing mood disorders. He emphasised the need for a shift in treatment approaches given the strong preliminary evidence suggesting a connection between circadian misalignment and mental health conditions.
While the study points to the possibility of treating mood disorders by adjusting body clocks, the researchers caution that internal jet lag is not established as a direct cause of poor mental health. Further investigation is warranted to deepen the understanding of this relationship.
This research opens the door to innovative strategies for addressing mental health issues in young Australians, with potential benefits for many individuals grappling with depression and anxiety. For support, individuals can reach out to Lifeline at 13 11 14 or Beyond Blue at 1300 22 4636.