Recent research has uncovered a potential benefit of non-steroidal anti-inflammatory drugs (NSAIDs) beyond their traditional use for alleviating pain. A comprehensive study published in the Journal of the American Geriatrics Society indicates that prolonged use of NSAIDs may lower the risk of developing dementia. Common over-the-counter medications like aspirin, ibuprofen, and Voltaren, which many people keep at home, could play a role in brain health.
The two-decade-long study involved over 11,000 participants aged 55 and above, revealing that those who consumed these anti-inflammatories consistently for over two years had an 18% reduced risk of dementia compared to those who did not take them. Geriatrician Paul Yates from Austin Health and the University of Melbourne emphasised the growing understanding of dementia’s links to inflammation in the body, which suggests that anti-inflammatories could have therapeutic potential in managing or reducing dementia risks.
However, the findings do indicate a contrasting trend for short-term NSAID users, who exhibited a slightly higher incidence of dementia. This could be attributed to the possibility that their inflammatory conditions were not as closely monitored and managed as those using NSAIDs long-term. Interestingly, the study highlighted that higher dosages of the medication did not correlate with increased benefits; rather, it was the duration of use that was key.
While these findings are noteworthy, experts advise individuals not to begin taking NSAIDs in hopes of preventing dementia without consulting a healthcare professional. If there are concerns about dementia risks, it is essential to discuss them with your GP to explore appropriate and effective strategies for maintaining cognitive health.